But some people have a delayed allergic reaction to certain drugs. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. The Injectafer dosage your doctor prescribes will depend on your body weight. With IV infusion, the drug is given as a slow drip into your vein over a period of time. The iron released by this drug does pass into human breast milk. However, side effects at the 150 mg dose may indicate that you might not . Venofer (iron sucrose) Uses, Dosage, Side Effects - Drugs.com But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. upper respiratory infection. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Your doctor will be able to see how Venofer is working by reviewing your blood tests. Their medical staff can help you set up another time to receive your Injectafer dose. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. I actually was constipated after my 3rd but didn't think anything of it. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Injectafer isnt a medication that youll take regularly on a schedule. Venofer (iron sucrose) dosing, indications, interactions, adverse This allows them to manage any side effects that you may have following your dose. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. intense abdominal pain. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. The information provided is not intended to replace your healthcare provider's medical advice. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. (IV iron is absorbed by the body more rapidly than oral iron.) SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. There isnt a known interaction between Injectafer and alcohol. Its given by either intravenous (IV) infusion or slow IV injection. It is given into a vein for a period of time. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. People with IDA have low blood levels of hemoglobin. Do not share your drugs with others and do not take anyone else's drugs. Here's some detail on certain side effects this drug may cause. Venofer may cause significant hypotension (decreased blood pressure). And this person had gotten their first dose of the drug without having an allergic reaction. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). As with most drugs, some people can have an allergic reaction after taking Injectafer. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. The drug helps increase your hemoglobin level back to a value thats within the normal range. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Selected from data included with permission and copyrighted by First Databank, Inc. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Call your doctor for medical advice about side effects. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. There are currently no generic forms of either drug. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. I used to get a different type but my . In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Does Venofer Vial interact with other drugs you are taking? (See also Notes section.). endobj Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. Its not known how often people taking a treatment other than Injectafer had diarrhea. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Available for Android and iOS devices. 3 0 obj Canada residents can call a provincial poison control center. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. It depends. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. (Hemoglobin is a protein thats found inside your red blood cells.). For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Cancer patients who have anemia and are taking an ESA. Allergic reactions typically occur the first time your body is exposed to a drug. Theyll recommend how to manage your condition. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. In the US - Call your doctor for medical advice about side effects. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. 2005 - 2023 WebMD LLC. fever. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Venofer - Iron sucrose uses, dose and side effects - zeepedia.com What is Venofer? signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. These lists dont include all possible side effects. <> The benefit of treating your condition during pregnancy may outweigh any risks. You may report side effects to the FDA at 1-800-332-1088. This is not a complete list of side effects and others may occur. Last reviewed . Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. On day three I had a headache and felt heavy/exhausted, which lasted a few days. Anyone had an adverse reaction to Venofer (iron sucrose) and how long Use of the term female in this article refers to sex assigned at birth. Does Venofer Vial interact with other medications? Keep all drugs out of the reach of children and pets. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Depending on your anemia symptoms, your weight changes may be different than those described here. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. You will be watched closely by your doctor for 30 minutes after each dose. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. No, you wont need to take iron pills while youre using Injectafer. During Injectafer treatment, your doctor will likely order blood tests. other treatments you receive, you will need to go back for several treatments with Venofer. Theyll likely have you stop taking the pills while youre using Injectafer. It is very important that your doctor check you closely while you are receiving this medicine. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. This medication is given by injection into a vein as directed by your doctor. You should always consult your doctor or another healthcare professional before taking any medication. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. It can be given as a slow injection over 2 to 5 minutes or as an infusion. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Some may be a better fit for you than others. After the infusion, you can drive yourself home and return to your usual activities. It may also cause nervousness, restlessness, and difficulty sleeping in some people. 2. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Iron Infusion: Benefits, Side Effects, and What to Expect - Healthline This is not a list of all drugs or health problems that interact with this medicine. Injectafer and Venofer are both brand-name drugs. These nutrients include iron, vitamin B12, and folate. (A generic drug is an exact copy of the active drug in a brand-name medication.) And this can lead to anemia, including IDA. What to Know About Iron Infusions for Anemia Treatment - GoodRx Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Here we look at how Injectafer and Venofer are alike and different. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Are there side effects from an MRI? - Coalitionbrewing.com They can recommend if this is safe for you to do. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Potential injection site discoloration has happened. It belongs to a class of medications called iron replacement products. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Others last much longer (even a lifetime), which can be quite traumatizing to people. (A class of medications describes a group of drugs that work in the same way.). Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug.
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